If you were to take biochemistry, you would first have to take a semester of course is to learn just enough about biochemistry to understand what's going on at. LECTURE NOTES. For Health Science Students. Medical Biochemistry. Solomon Adugna, Lakshmi Ahuja Mekonnen Alemu, Tsehayneh. Kelemu, Henok Tekola. Download this Biochemistry A study guide to get exam ready in less time! Study guide uploaded on Dec 17, Page(s).
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These seven volumes of Lecture Notes represent a yearlong effort on the part of the Kaplan. Medicalfacultyto update our curriculum to reflectthe. PDF | Gianluca Tell and others published Biochemistry and Molecular Biology Notes. COURSE INFORMATION AND MATERIALS. To access the PDF files, you'll need Adobe Acrobat. If you need to download it to your own computer for free, here.
You are on page 1of 11 Search inside document Water I. Properties of Water A. Hydrogen bonding is responsible for other properties. High surface tension. High specific heat and therefore: 1.
High heat of fusion and vaporization 1. If water didnt hydrogen bond it would boil at a much lower temperature and freeze at a much higher temperature. Most dense at 4C.
Universal solvent H. Great lubricant II. Buffers A. Can the body withstand major shifts in pH? The pH of human blood ranges between 7. The Sodium bicarbonate-carbonic acid system 1. What happens when a strong acid enters the blood stream? What happens when a strong base enters the blood stream? Hydrocarbons A. Composed of hydrogen and carbon and form the backbone of most organic molecules.
Have a lot of stored energy.
Insoluble in water, Why? Alcohols R-OH A. A hydroxyl group. Soluble in water. Also good fuels. Carboxylic Acid organic acid A.
Amines R- NH2 A. Soluble in water B. Alkaline a proton acceptor C.
Example: NH3 ammonia VI. Small ones 4 carbons or less are soluble in water B.
Aromatic aldehydes are used as artificial scents, see example. Examples of aldehydes: Formaldehyde VII. Ketones A. Also very aromatic. Many steroids contain ketone groups. Examples Testosterone Acetone Foodstuffs I. Carbohydrates composed of C, H and O. Functions 1. Roughage 3.
Structural backbone of plant cell walls wood. Structure 1. Or aldose or ketose what functional group? Monosaccharides 1. Disaccharides 1. How does a disaccharide form? Polysaccharides 1.
Types all three are composed of chains of glucose 2. Starch a Storage form of glucose in plants. Amylose g The amylopectin molecule can contain between 1, -6, glucose units with 1,6 linkages about every 30 glucose units. Glycogen a Storage form of sugar in animals. Cellulose a Structural carbohydrate, forms cell wall in plants. The chains are attracted to each other, thus preventing enzymes from attacking the molecule.
Chitin a A polysaccharide that contains nitrogen. Lipids A. Padding and insulation protection 2. Form backbone of some hormones. Store fat soluble vitamins A,D,E, and K 5. Component of all cell membranes.
All lipids have a high hydrogen to carbon ratio with few oxygens. What functional group would this be? What properties would you expect?
There are five common lipids: fats, oils, waxes, phospholipids, and steroids. Fats 1. Fats are fatty acid esters of glycerol.
Saturated vs unsaturated fatty acids a Saturated 1 no carbon to carbon double bonds 2 comes from animals 3 solid at room temp. Essential fatty acids: Linoleic and linolenic 4. Formation of a fat D. Waxes 1. Waxes are similar to fats but are composed of much larger fatty acids E. Protein puri fication. Nucleic aci ds.
Dogma is an established belief or doctrine: Should have a very good scientific basis. DNA should b e dupli cable. Chromatin has a very important role in the expression of DNA. Little pieces of RNA that will bind to the sense stran d and block transcription. Mods with phosphate, acetyl, methyl groups attached to pns to regu late availability of pns for.
Post translational modification. Modifications to the dogma. The sum of in heritable potential. The sum of observabl e charac teristics. Therefore, defects i n DNA can l ead to defects in p ns…lead to p roblems. Only of you h ave the ri ght genotype. Totally i rrelevant. Genotype vs. Can you have an 8 -pack. This week: Saturd ay oct 26 7- Other admin notes:. Topic 1: The Central Dogma.
Tuesday, September 10, 3. Biochemistry Page 1. Unlock Document Start your 2 days free trial.
They are the building blocks of pn s. Amino group, carboxyl group, hydrogen, and -R group. Since 4 different groups are attached to a carbon ato m, stereoisomerism is possib le. Only the L-forms are incorporated in to pns. General structur e:. Changes h as the [H] changes because o f the associatio n of hydrogen ions with the groups.
They have a net charge derived from the ionization of weakly acidic or basic groups. This equil ibrium is ch aracterized by a constant Ka for each individual group. Recall that fo r a weak acid:. Carboxyl g roup is depr otonated -1 , but the am in o group is still p ro tonated with a.